They found that patients who consumed cannabis daily or weekly were less sensitive to many different types of anesthetic drugs compared to patients who never used it. What was interesting was they discovered that it required a 14% higher dose of fentanyl, 220% more propofol, and 20% more midazolam to effectively sedate the patients for the endoscopy. Because the nature of the procedure means that very sensitive orifices in the body will be affected during endoscopy, a good amount of anesthesia is needed for proper sedation.
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